A grant from the National Institute on Disability and Rehabilitation Research has been awarded in the amount of $4.9 million to Carolinas Rehabilitation to study the drug Amantadine in the treatment of traumatic brain injury. The study will conduct research to determine if the drug, which is used to bring TBI victims out of a coma, can be used to limit the irritability and aggression often associated with a brain injury. Physicians from Carolinas Rehabilitation were the first to discover that Amantadine might extend its usefulness. The grant will be used to repeat the physicians’ findings at multiple sites nationwide to determine Amantadine’s efficacy in treating the cognitive dysfunctions often associated with TBIs. Carolinas Rehabilitation is a division of Carolinas HealthCare System of Charlotte, North Carolina which owns, leases or manages 23 hospitals in the Carolinas.