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Clinical Trial to use Hypertonic Saline Solution in TBI

Orange County California will be at the center of a new clinical trial using a hypertonic saline solution by emergency workers and medical doctors in the treatment and resuscitation method for victims of severe traumatic brain injury. The group labeled The Orange County Resuscitation Outcomes Consortium includes hospitals, healthcare agencies and fire departments. The ROC group’s effort will attempt to substantiate previous studies that have shown that hypertonic saline safely and effectively decreases inflammation in brain traumas. A similar approach was used with considerable success with the Buffalo Bill’s Tight End Kevin Everett after he suffered a spinal cord injury during a football game. The Orange County ROC trial will differ from other clinical trials because many of its participants will not be able to give consent or have family nearby to do so. Consent is required for all clinical studies, although federal law allows for exceptions if the safety of the product to be used has been proven in previous trials and if study leaders conduct community outreach discussions and opt-out measures for those who do not want to participate.

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