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August 30, 2007

NSF Research Yields Few Clues into Disease

Since 1997, the medical community has been trying to determine the cause of Nephrogenic Systemic Fibrosis (NSF). NSF is also known as Nephrogenic Fibrosing Dermopathy. It is a rare and little understood disease that affects people with kidney problems. Since the first cases were documented, research into NSF has provided few clues into its cause, and even fewer as to its treatment. Most patients eventually diagnosed with NSF are first found to have high blood pressure, which is followed by burning, itching, swelling and hardening of the skin. Other symptoms include red or dark patches on the skin; pain deep in the hip bones or ribs and muscle weakness. NSF can progress to the point of causing severe stiffness in joints, and can eventually lead to death. The progression of the disease can be slow and can take several years for all of the symptoms to appear. However, some patients have a form that progresses so quickly that they often die of complications brought on by the disease.

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