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March 08, 2007

Are Ortho Evra Patch users at more risk for cancer?

According to the FDA found on their label site describing Ortho Evra or Patch use numerous epidemiological studies give conflicting reports on the relationship between breast cancer and COC (combination oral contraceptives) use. The risk of having breast cancer diagnosed may be slightly increased among current and recent users of the combination oral contraceptives. However, this excess risk appears to decrease over time after COC discontinuation and by 10 years after cessation the increased risk disappears. With a 60% increase of hormones released through Ortho Evra does that increase cancer risk? Some studies report an increased risk with duration of use while other studies do not and no consistent relationships have been found with dose of type of steroid. Some studies have found a small increase in risk for women who first use COCs before age 20. Most studies show a similar pattern of risk with COC use regardless of a womans’s reproductive history or her family breast cancer history.

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